Extracellular traps from myeloid cells as therapeutic targets in traumatic heterotopic ossification

Musculoskeletal injuries, including tendon and ligament trauma, can lead to ectopic bone formation near the site of injury, and there are few effective treatments available to prevent this traumatic heterotopic ossification (HO). Here, Jiang et al. found ...
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A yeast-expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates

Ongoing severe acute respiratory syndrome coronavirus–2 (SARS-CoV-2) vaccine development is focused on identifying stable, cost-effective, and accessible candidates for global use, specifically in low- and middle-income countries. Here, we report the effi...
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A Caenorhabditis elegans spatiotemporal proximity atlas reveals the MAPK p38 as a generator of phenotypic plasticity in vivo

The mitogen-activated protein kinase (MAPK) p38 contributes to developmental and homeostatic processes and plays a key role in stress adaptation. Using in vivo proximity labeling, Yuan et al. investigated signaling networks of the Caenorhabditis elegans p...
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